Phosphoenolpyruvate carboxykinase (diphosphate)
| Phosphoenolpyruvate carboxykinase (diphosphate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Phosphoenolpyruvate carboxykinase (pyrophosphate) homodimer, Actinomyces israelii | |||||||||
| Identifiers | |||||||||
| EC no. | 4.1.1.38 | ||||||||
| CAS no. | 2598306 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Phosphoenolpyruvate carboxykinase (diphosphate) (EC 4.1.1.38) is an enzyme with systematic name diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming). This enzyme catalyses the following chemical reaction
- diphosphate + oxaloacetate phosphate + phosphoenolpyruvate + CO2
This enzyme also catalyses the reaction:
- phosphoenolpyruvate + GTP + CO2 pyruvate + GDP.
It is transcriptionally upregulated in the liver by glucagon.