Phyre

Phyre2
Developer(s)
  • Lawrence Kelley
  • Bob Maccallum
  • Benjamin Jefferys
  • Alex Herbert
  • Riccardo Bennett-Lovsey
  • Michael Sternberg
Stable release
2.0 / 23 February 2011 (2011-02-23)
Written in
Available inEnglish
TypeBioinformatics tool for protein structure prediction
LicenseCreative Commons Attribution-2.0
Websitewww.sbg.bio.ic.ac.uk/phyre2

Phyre and Phyre2 (Protein Homology/AnalogY Recognition Engine; pronounced as fire) are free web-based services for protein structure prediction. Phyre is among the most popular methods for protein structure prediction having been cited over 1,500 times. Like other remote homology recognition techniques (see protein threading), it is able to regularly generate reliable protein models when other widely used methods such as PSI-BLAST cannot. Phyre2 has been designed to ensure a user-friendly interface for users inexpert in protein structure prediction methods. Its development is funded by the Biotechnology and Biological Sciences Research Council.