Pittsburgh compound B

Pittsburgh compound B
Names
Preferred IUPAC name
2-{4-[(11C)Methylamino]phenyl}-1,3-benzothiazol-6-ol
Other names
PiB
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-7-6-11(17)8-13(12)18-14/h2-8,15,17H,1H3/i1-1 N
    Key: ZQAQXZBSGZUUNL-BJUDXGSMSA-N N
  • InChI=1/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-7-6-11(17)8-13(12)18-14/h2-8,15,17H,1H3/i1-1
    Key: ZQAQXZBSGZUUNL-BJUDXGSMEE
  • [11CH3]NC1=CC=C(C=C1)C2=NC3=C(S2)C=C(C=C3)O
Properties
C14H12N2OS
Molar mass 256.32 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Pittsburgh compound B (PiB) is a radioactive analog of thioflavin T, which can be used in positron emission tomography scans to image beta-amyloid plaques in neuronal tissue. Due to this property, Pittsburgh compound B may be used in investigational studies of Alzheimer's disease.