Plakophilin-1

PKP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XM9
Identifiers
Aliases	PKP1, B6P, plakophilin 1, EDSFS
External IDs	OMIM: 601975; MGI: 1328359; HomoloGene: 253; GeneCards: PKP1; OMA:PKP1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	201,332,993 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	135,846,945 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; skin of abdomen; ; skin of leg; ; skin of thigh; ; gums; ; gingival epithelium; ; vulva; ; skin of hip; ; human penis; ; nipple;
	Top expressed in
	skin of external ear; ; hair follicle; ; lip; ; skin of back; ; esophagus; ; conjunctival fornix; ; skin of abdomen; ; molar; ; corneal stroma; ; condyle;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of skin epidermis; protein binding; intermediate filament binding; signal transducer activity; lamin binding; cadherin binding;
Cellular component	intracellular membrane-bounded organelle; cell junction; intermediate filament; nucleoplasm; plasma membrane; nucleus; desmosome; cornified envelope; ficolin-1-rich granule membrane; messenger ribonucleoprotein complex; cytoplasm; cell-cell junction;
Biological process	multicellular organism development; intermediate filament bundle assembly; signal transduction; cell adhesion; keratinization; neutrophil degranulation; cornification; positive regulation of gene expression; negative regulation of mRNA catabolic process; cell-cell adhesion; cell-cell junction assembly;
	Sources:Amigo / QuickGO
Orthologs
	5317
	18772
	ENSG00000081277
	ENSMUSG00000026413
	Q13835
	P97350
	NM_001005337; NM_000299
	NM_019645; NM_001313701
	NP_000290; NP_001005337
	NP_001300630; NP_062619
	Wikidata
View/Edit Human	View/Edit Mouse

Plakophilin-1 is a protein that in humans is encoded by the PKP1 gene.