Polyptychodon
| Polyptychodon Temporal range: Late Cretaceous,  | |
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| P. interruptus jaw with tooth | |
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| Genus: | †Polyptychodon Owen, 1841 | 
| Binomial name | |
| †Polyptychodon interruptus Owen, 1841 | |
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Polyptychodon (meaning 'many-folded tooth') is a genus of pliosaurid found in Middle-Late Cretaceous marine deposits in southern England, France and Argentina. It has been considered a nomen dubium in a 2016 review.