Primase
| Toprim domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Toprim | ||||||||
| Pfam | PF01751 | ||||||||
| Pfam clan | Toprim-like | ||||||||
| InterPro | IPR006171 | ||||||||
| SCOP2 | 2fcj / SCOPe / SUPFAM | ||||||||
| |||||||||
| Toprim catalytic core | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Toprim_N | ||||||||
| Pfam | PF08275 | ||||||||
| InterPro | IPR013264 | ||||||||
| SCOP2 | 1dd9 / SCOPe / SUPFAM | ||||||||
| |||||||||
| AEP DNA primase, small subunit | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | DNA_primase_S | ||||||||
| Pfam | PF01896 | ||||||||
| Pfam clan | AEP | ||||||||
| InterPro | IPR002755 | ||||||||
| SCOP2 | 1g71 / SCOPe / SUPFAM | ||||||||
| |||||||||
| AEP DNA primase, large subunit | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | DNA_primase_lrg | ||||||||
| Pfam | PF04104 | ||||||||
| Pfam clan | CL0242 | ||||||||
| InterPro | IPR007238 | ||||||||
| SCOP2 | 1zt2 / SCOPe / SUPFAM | ||||||||
| |||||||||
DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA (or DNA in some living organisms) segment called a primer complementary to a ssDNA (single-stranded DNA) template. After this elongation, the RNA piece is removed by a 5' to 3' exonuclease and refilled with DNA.