Prodipine

Prodipine
Clinical data
Other names	BY-101; 1-Isopropyl-4,4-diphenylpiperidine
Routes of; administration	Oral, intravenous injection
Drug class	Antiparkinsonian agents
Identifiers
	IUPAC name 4,4-diphenyl-1-propan-2-ylpiperidine;
CAS Number	31314-38-2;
PubChem CID	65775;
ChemSpider	59195;
UNII	51567MYG7V;
ChEMBL	ChEMBL277382;
CompTox Dashboard (EPA)	DTXSID20185247 ;
Chemical and physical data
Formula	C20H25N
Molar mass	279.427 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3;
	InChI InChI=1S/C20H25N/c1-17(2)21-15-13-20(14-16-21,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17H,13-16H2,1-2H3; Key:CFOOTBBXHJHHMT-UHFFFAOYSA-N;

Prodipine (INNTooltip International Nonproprietary Name; developmental code name BY-101) is an experimental antiparkinsonian agent of the 4,4-diphenylpiperidine series related to budipine which was never marketed. It was the predecessor of budipine and was similarly found to be effective in the treatment of Parkinson's disease. However, prodipine produced side effects including gastrointestinal adverse effects, nausea and vomiting, and hypotension. Due to the nausea and vomiting with the oral form, it could only be tolerated with intravenous administration. As a result, budipine, which had fewer side effects, was developed instead.

Clinical data

Other names	BY-101; 1-Isopropyl-4,4-diphenylpiperidine
Routes of administration	Oral, intravenous injection
Drug class	Antiparkinsonian agents
Identifiers
IUPAC name 4,4-diphenyl-1-propan-2-ylpiperidine
CAS Number	31314-38-2
PubChem CID	65775
ChemSpider	59195
UNII	51567MYG7V
ChEMBL	ChEMBL277382
CompTox Dashboard (EPA)	DTXSID20185247
Chemical and physical data
Formula	C₂₀H₂₅N
Molar mass	279.427 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3
InChI InChI=1S/C20H25N/c1-17(2)21-15-13-20(14-16-21,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17H,13-16H2,1-2H3 Key:CFOOTBBXHJHHMT-UHFFFAOYSA-N