Profenamine

Profenamine
Clinical data
Trade namesParsidol, Parsidan, Parkisol, Parkin
AHFS/Drugs.comInternational Drug Names
ATC code
Pharmacokinetic data
Protein binding93%
Elimination half-life1 to 2 hours
Identifiers
  • N,N-Diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.566
Chemical and physical data
FormulaC19H24N2S
Molar mass312.48 g·mol−1
3D model (JSmol)
  • S2c1ccccc1N(c3c2cccc3)CC(N(CC)CC)C
  • InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3 Y
  • Key:CDOZDBSBBXSXLB-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

Profenamine (INN; also known as ethopropazine (BAN); sold under the trade name Parsidol and others) is a phenothiazine derivative used as an antiparkinsonian agent that has anticholinergic, antihistamine, and antiadrenergic actions. It is also used in the alleviation of the extrapyramidal syndrome induced by drugs such as other phenothiazine compounds, but, like other compounds with antimuscarinic properties, is of no value against tardive dyskinesia.