Prolyl endopeptidase

PREP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3DDU
Identifiers
Aliases	PREP, PE, PEP, prolyl endopeptidase
External IDs	OMIM: 600400; MGI: 1270863; HomoloGene: 2042; GeneCards: PREP; OMA:PREP - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	105,454,062 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gastrocnemius muscle; ; mucosa of transverse colon; ; rectum; ; triceps brachii muscle; ; muscle of thigh; ; Skeletal muscle tissue of rectus abdominis; ; glutes; ; mucosa of sigmoid colon; ; biceps brachii;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	serine-type exopeptidase activity; peptidase activity; serine-type peptidase activity; serine-type endopeptidase activity; protein binding; hydrolase activity; endopeptidase activity; oligopeptidase activity;
Cellular component	membrane; nucleus; cytoplasm; cytosol;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	5550
	19072
	ENSG00000085377
	ENSMUSG00000019849
	P48147
	Q9QUR6
	NM_002726
	NM_011156
	NP_002717
	NP_035286
	Wikidata
View/Edit Human	View/Edit Mouse

Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene.