Propionyl chloride
| Names | |
|---|---|
| Preferred IUPAC name
Propanoyl chloride | |
| Other names
Propionic chloride; propionic acid chloride (1:1) | |
| Identifiers | |
3D model (JSmol) |
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| ECHA InfoCard | 100.001.064 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C3H5ClO | |
| Molar mass | 92.52 g·mol−1 |
| Appearance | colorless liquid |
| Density | 1.0646 g/cm3 |
| Melting point | −94 °C (−137 °F; 179 K) |
| Boiling point | 80 °C (176 °F; 353 K) |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
Corrosive, flammable; highly toxic |
| Flash point | 54 °C (129 °F; 327 K) |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
100 mg/kg (rat, oral) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
Propionyl chloride (also propanoyl chloride) is the organic compound with the formula CH3CH2C(O)Cl. It is the acyl chloride derivative of propionic acid. It undergoes the characteristic reactions of acyl chlorides. It is a colorless, corrosive, volatile liquid.
It is used as a reagent for organic synthesis. In derived chiral amides and esters, the methylene protons are diastereotopic.
There have been efforts to schedule Propionyl chloride as a DEA List 1 Chemical as it can be used to synthesize fentanyl.