Propylhexedrine

Propylhexedrine
Left: (S)-Propylhexedrine
Right: (R)-Propylhexedrine
Clinical data
Trade namesBenzedrex, Obesin, Dristan Inhaler, and others
Other names1-cyclohexyl-2-methylaminopropane
AHFS/Drugs.comMonograph
Pregnancy
category
  • C
Routes of
administration
Medical: Intranasal (inhaler)
Recreational: Oral, parenteral
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life4 ± 1.5 hours
Identifiers
  • (±)-1-cyclohexyl-N-methylpropan-2-amine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.002.673
Chemical and physical data
FormulaC10H21N
Molar mass155.285 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • N(C(CC1CCCCC1)C)C
  • InChI=1S/C10H21N/c1-9(11-2)8-10-6-4-3-5-7-10/h9-11H,3-8H2,1-2H3 Y
  • Key:JCRIVQIOJSSCQD-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

Propylhexedrine, sold under the brand name Benzedrex among others, is an alkylamine primarily utilized as a topical nasal decongestant. Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. Propylhexedrine was first used medically in 1949, with the release of Benzedrex by Smith, Kline & French, and it has been used, mainly within the United States, since then.