Avenida Juan Ponce de León

Highway 25
Highway 25
Ruta 25
Avenida Juan Ponce de León
Route information
	Maintained by Puerto Rico DTPW
Length	11.1 km (6.9 mi)
Major junctions
South end	PR-3 in Pueblo–Hato Rey Sur
	PR-17 in Universidad–Hato Rey Sur; PR-41 in Hato Rey Central–Hato Rey Norte; PR-23 in Hato Rey Central–Hato Rey Norte; PR-36 in Santurce; PR-37 Santurce; PR-22 in Santurce; PR-2 in Santurce; PR-39 in Santurce; PR-1 / PR-16 / PR-26 in Santurce; PR-1 / PR-25P in San Juan Antiguo;
North end	Calle Fortaleza / Calle Recinto Sur in San Juan Antiguo
Location
Country	United States
Territory	Puerto Rico
Municipalities	San Juan
Highway system
	Roads in Puerto Rico; List;

Avenida Juan Ponce de León (Juan Ponce de León Avenue), also known as Avenida de la Constitución (Constitution Avenue), and coextensive as Puerto Rico Highway 25 (PR-25) along its entire length, is one of the main thoroughfares in San Juan, the capital municipality of Puerto Rico. Named after Juan Ponce de León, the Spanish conquistador who led the European colonization of the archipelago in 1508 after its discovery by Christopher Columbus during his second voyage in 1493, it connects the historic quarter of Old San Juan in San Juan Islet with the residential and resort barrio of Santurce, the business center of Hato Rey, and the commercial and residential district of Río Piedras in the main island. It is one of the oldest roadways in Puerto Rico, as some sections are dated to at least 1519.