Quinupristin/dalfopristin
< Quinupristin
Quinupristin (top) and dalfopristin (bottom) | |
| Combination of | |
|---|---|
| Quinupristin | Streptogramin antibiotic |
| Dalfopristin | Streptogramin antibiotic |
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| Routes of administration | IV |
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Quinupristin/dalfopristin, or quinupristin-dalfopristin, (pronunciation: kwi NYOO pris tin / dal FOE pris tin) (trade name Synercid) is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium.
Quinupristin and dalfopristin are both streptogramin antibiotics, derived from pristinamycin. Quinupristin is derived from pristinamycin IA; dalfopristin from pristinamycin IIA. They are combined in a weight-to-weight ratio of 30% quinupristin to 70% dalfopristin. Discontinued 2022, there are no other manufacturers of this medication.