RAB27A

RAB27A
Identifiers
Aliases	RAB27A, GS2, HsT18676, RAB27, RAM, member RAS oncogene family
External IDs	OMIM: 603868; MGI: 1861441; HomoloGene: 3069; GeneCards: RAB27A; OMA:RAB27A - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	55,319,113 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	73,004,911 bp
RNA expression pattern
	Top expressed in
	trabecular bone; ; monocyte; ; lower lobe of lung; ; bone marrow; ; mucosa of sigmoid colon; ; bone marrow cells; ; blood; ; secondary oocyte; ; retinal pigment epithelium; ; rectum;
	Top expressed in
	granulocyte; ; retinal pigment epithelium; ; epithelium of stomach; ; lacrimal gland; ; iris; ; salivary gland; ; islet of Langerhans; ; parotid gland; ; zygote; ; left lung lobe;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein domain specific binding; GDP binding; GTP binding; myosin V binding; protein binding; GTPase activity;
Cellular component	Weibel-Palade body; endosome; late endosome; Golgi apparatus; multivesicular body membrane; exocytic vesicle; secretory granule membrane; membrane; melanosome; photoreceptor outer segment; secretory granule; dendrite; apical plasma membrane; lysosome; extracellular exosome; extracellular region; cytosol; melanosome membrane; specific granule lumen; synapse;
Biological process	positive regulation of reactive oxygen species biosynthetic process; natural killer cell degranulation; protein targeting; positive regulation of phagocytosis; antigen processing and presentation; multivesicular body sorting pathway; pigment granule localization; blood coagulation; melanosome localization; pigment granule transport; positive regulation of gene expression; multivesicular body organization; melanosome transport; positive regulation of constitutive secretory pathway; synaptic vesicle transport; complement-dependent cytotoxicity; pigmentation; cytotoxic T cell degranulation; exosomal secretion; positive regulation of exocytosis; melanocyte differentiation; vesicle-mediated transport; positive regulation of regulated secretory pathway; exocytosis; neutrophil degranulation; intracellular protein transport; Rab protein signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	5873
	11891
	ENSG00000069974
	ENSMUSG00000032202
	P51159
	Q9ERI2
	NM_004580; NM_183234; NM_183235; NM_183236
	NM_001301230; NM_001301232; NM_023635
	NP_004571; NP_899057; NP_899058; NP_899059
	NP_001288159; NP_001288161; NP_076124
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene.