Ras-related protein Rab-4B is a protein that in humans is encoded by the RAB4B gene.
Ras-related protein Rab-4B is involved in the vesicle recycling process of endocytosis. Eukaryotic cells uptake cargo from their external environment via donor vesicle budding and fusion of the bud with its target cell membrane. Many proteins are required to maintain homeostasis through this process and to tightly regulate the transport, docking and recycling of materials within the cell. Rab-4B proteins contribute to the regulation of endocytotic recycling in order to control vesicular trafficking.