RAD1 homolog

RAD1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3A1J, 3G65, 3GGR
Identifiers
Aliases	RAD1, HREC1, RAD1 homolog, RAD1 checkpoint DNA exonuclease
External IDs	OMIM: 603153; MGI: 1316678; HomoloGene: 37695; GeneCards: RAD1; OMA:RAD1 - orthologs
EC number	3.1.11.2
Gene location (Human)
Chr.	Chromosome 5 (human)
End	34,918,989 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	10,499,149 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; nipple; ; urethra; ; visceral pleura; ; renal medulla; ; superior surface of tongue; ; ventral tegmental area; ; pylorus; ; cardia; ; Achilles tendon;
	Top expressed in
	embryo; ; epiblast; ; spermatocyte; ; ventricular zone; ; morula; ; endocardial cushion; ; ectoderm; ; otic vesicle; ; otic placode; ; medial ganglionic eminence;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	damaged DNA binding; exodeoxyribonuclease III activity; protein binding; 3'-5' exonuclease activity; nuclease activity; exonuclease activity; hydrolase activity;
Cellular component	intracellular membrane-bounded organelle; chromosome; nucleoplasm; checkpoint clamp complex; nucleus;
Biological process	substantia nigra development; DNA damage checkpoint signaling; cellular response to DNA damage stimulus; DNA replication; meiotic recombination checkpoint signaling; cellular response to ionizing radiation; nucleic acid phosphodiester bond hydrolysis; regulation of signal transduction by p53 class mediator; DNA repair;
	Sources:Amigo / QuickGO
Orthologs
	5810
	19355
	ENSG00000113456
	ENSMUSG00000022248
	O60671
	Q9QWZ1
	NM_001033673; NM_002853; NM_133282; NM_133377
	NM_001289447; NM_001289448; NM_011232
	NP_002844
	NP_001276376; NP_001276377; NP_035362
	Wikidata
View/Edit Human	View/Edit Mouse

Cell cycle checkpoint protein RAD1 is a protein that in humans is encoded by the RAD1 gene.