Retinoic acid receptor beta

RARB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HRA, 1XAP, 4DM6, 4DM8, 4JYG, 4JYH, 4JYI
Identifiers
Aliases	RARB, HAP, MCOPS12, NR1B2, RRB2, RARbeta1, retinoic acid receptor beta, RARbeta
External IDs	OMIM: 180220; MGI: 97857; HomoloGene: 68100; GeneCards: RARB; OMA:RARB - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	25,597,932 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	6,038,924 bp
RNA expression pattern
	Top expressed in
	Epithelium of choroid plexus; ; palpebral conjunctiva; ; buccal mucosa cell; ; right lung; ; gonad; ; nucleus accumbens; ; caudate nucleus; ; olfactory zone of nasal mucosa; ; right auricle of heart; ; Achilles tendon;
	Top expressed in
	olfactory tubercle; ; nucleus accumbens; ; wall of esophagus; ; stroma of kidney; ; mucosa of esophagus; ; epithelium of esophagus; ; genital tubercle; ; globus pallidus; ; abdominal wall; ; atrioventricular valve;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; zinc ion binding; metal ion binding; steroid hormone receptor activity; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein-containing complex binding; retinoid X receptor binding; transcription cis-regulatory region binding; transcription factor binding; nuclear receptor coactivator activity; signaling receptor activity; nuclear receptor activity;
Cellular component	cytoplasm; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex;
Biological process	growth plate cartilage development; positive regulation of transcription by RNA polymerase II; neurogenesis; ureteric bud development; regulation of transcription, DNA-templated; negative regulation of cartilage development; multicellular organism growth; embryonic eye morphogenesis; positive regulation of programmed cell death; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; retinal pigment epithelium development; transcription, DNA-templated; outflow tract septum morphogenesis; negative regulation of chondrocyte differentiation; retinoic acid receptor signaling pathway; regulation of myelination; retina development in camera-type eye; positive regulation of neuron differentiation; positive regulation of cell population proliferation; positive regulation of apoptotic process; ventricular cardiac muscle cell differentiation; transcription initiation from RNA polymerase II promoter; bone development; embryonic digestive tract development; striatum development; signal transduction; negative regulation of cell population proliferation; glandular epithelial cell development; steroid hormone mediated signaling pathway; embryonic hindlimb morphogenesis; liver development; multicellular organism development; hormone-mediated signaling pathway; cell differentiation; response to retinoic acid; response to lipid; gland development; bone morphogenesis; epithelium development; cellular response to retinoic acid;
	Sources:Amigo / QuickGO
Orthologs
	5915
	218772
	ENSG00000077092
	ENSMUSG00000017491
	P10826; Q5QHG3
	P22605
NM_000965; NM_001290216; NM_001290217; NM_001290266; NM_001290276;
	NM_001290277; NM_001290300; NM_016152
	NM_001289760; NM_001289761; NM_001289762; NM_011243
NP_000956; NP_001277145; NP_001277146; NP_001277195; NP_001277205;
	NP_001277206; NP_001277229; NP_057236; NP_001277146.1; NP_001277205.1; NP_057236.1
	NP_001276689; NP_001276690; NP_001276691; NP_035373
	Wikidata
View/Edit Human	View/Edit Mouse

Retinoic acid receptor beta (RAR-beta), also known as NR1B2 (nuclear receptor subfamily 1, group B, member 2) is a nuclear receptor that in humans is encoded by the RARB gene.