RASD1

RASD1
Identifiers
Aliases	RASD1, AGS1, DEXRAS1, MGC:26290, ras related dexamethasone induced 1
External IDs	OMIM: 605550; MGI: 1270848; HomoloGene: 7509; GeneCards: RASD1; OMA:RASD1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	17,496,395 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	59,855,770 bp
RNA expression pattern
	Top expressed in
	pericardium; ; renal medulla; ; anterior pituitary; ; middle temporal gyrus; ; pancreatic ductal cell; ; trachea; ; parotid gland; ; Brodmann area 23; ; right lobe of thyroid gland; ; cardiac muscle tissue of right atrium;
	Top expressed in
	brown adipose tissue; ; islet of Langerhans; ; suprachiasmatic nucleus; ; white adipose tissue; ; subcutaneous adipose tissue; ; medial dorsal nucleus; ; lactiferous gland; ; tunica adventitia of aorta; ; CA3 field; ; medial geniculate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity;
Cellular component	cytoplasm; perinuclear region of cytoplasm; plasma membrane; nucleus; sarcoplasmic reticulum; membrane;
Biological process	G protein-coupled receptor signaling pathway; negative regulation of transcription, DNA-templated; signal transduction; nitric oxide mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	51655
	19416
	ENSG00000108551
	ENSMUSG00000049892
	Q9Y272
	O35626
	NM_016084; NM_001199989
	NM_009026
	NP_001186918; NP_057168
	NP_033052
	Wikidata
View/Edit Human	View/Edit Mouse

Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. It is ubiquitously expressed in many tissues and cell types. As a member of the Ras superfamily of small G-proteins, RASD1 regulates signal transduction pathways through both G proteins and G protein-coupled receptors. RASD1 has been associated with several cancers. The RASD1 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.