RASGEF1C

RASGEF1C
Identifiers
Aliases	RASGEF1C, RasGEF domain family member 1C
External IDs	MGI: 1921813; HomoloGene: 17918; GeneCards: RASGEF1C; OMA:RASGEF1C - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	180,209,211 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	49,871,821 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; gonad; ; sural nerve; ; C1 segment; ; prefrontal cortex; ; cingulate gyrus; ; anterior cingulate cortex; ; right frontal lobe; ; testicle; ; Brodmann area 9;
	Top expressed in
	superior frontal gyrus; ; sciatic nerve; ; primary visual cortex; ; embryo; ; prefrontal cortex; ; olfactory bulb; ; neural tube; ; stria vascularis; ; embryo; ; piriform cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity;
Cellular component	intracellular anatomical structure;
Biological process	small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	255426
	74563
	ENSG00000146090
	ENSMUSG00000020374
	Q8N431
	Q9D300
	NM_001031799; NM_175062
	NM_029004; NM_001347462
	NP_778232
	NP_001334391; NP_083280
	Wikidata
View/Edit Human	View/Edit Mouse

RASGEF1C (Ras-Guanine Nucleotide Exchange Factor 1C) is a human protein coding gene that encodes the ras-GEF domain containing family member 1C protein. Human RASGEF1C functions in activating GTPase via Guanine Nucleotide Exchange and it has been found to be associated with neurodegenerative disorders.

The human RASGEF1C gene is a 108,417-base-pair long protein-coding gene located on the minus strand at 5q35.3.

The human RASGEF1C gene has 14 exons and transcribes a 2297-nucleotide mRNA transcript.