RASSF2

RASSF2
Identifiers
Aliases	RASSF2, CENP-34, RASFADIN, Ras association domain family member 2
External IDs	OMIM: 609492; MGI: 2442060; HomoloGene: 22840; GeneCards: RASSF2; OMA:RASSF2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	4,823,608 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	131,872,178 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; subthalamic nucleus; ; C1 segment; ; external globus pallidus; ; Medulla Oblongata; ; corpus callosum; ; pars reticulata; ; superior vestibular nucleus; ; internal globus pallidus; ; middle frontal gyrus;
	Top expressed in
	meninges; ; granulocyte; ; thymus; ; stroma of bone marrow; ; mesenteric lymph nodes; ; lumbar subsegment of spinal cord; ; spleen; ; blood; ; optic nerve; ; uterus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein kinase activity;
Cellular component	cytoplasm; nucleus; chromosome, centromeric region; kinetochore; chromosome; nucleoplasm; Golgi apparatus; cytosol; plasma membrane; protein-containing complex;
Biological process	positive regulation of JNK cascade; positive regulation of protein autophosphorylation; skeletal system development; regulation of osteoclast differentiation; negative regulation of peptidyl-serine phosphorylation; regulation of osteoblast differentiation; regulation of NIK/NF-kappaB signaling; homeostasis of number of cells; bone remodeling; ossification; negative regulation of NIK/NF-kappaB signaling; epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; signal transduction; positive regulation of protein kinase activity; protein stabilization; cell cycle; protein phosphorylation; regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	9770
	215653
	ENSG00000101265
	ENSMUSG00000027339
	P50749
	Q8BMS9
	NM_014737; NM_170774; NM_170773
	NM_175445; NM_001362866
	NP_055552; NP_739580
	NP_780654; NP_001349795
	Wikidata
View/Edit Human	View/Edit Mouse

Ras association domain-containing protein 2 is a protein that in humans is encoded by the RASSF2 gene.

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.