RBBP5

RBBP5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P4F, 4X8N, 4X8P, 5F6K, 5F6L
Identifiers
Aliases	RBBP5, RBQ3, SWD1, retinoblastoma binding protein 5, RB binding protein 5, histone lysine methyltransferase complex subunit
External IDs	OMIM: 600697; MGI: 1918367; HomoloGene: 3709; GeneCards: RBBP5; OMA:RBBP5 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	205,122,015 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	132,433,397 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; secondary oocyte; ; testicle; ; gonad; ; Achilles tendon; ; islet of Langerhans; ; ganglionic eminence; ; ventricular zone; ; stromal cell of endometrium; ; monocyte;
	Top expressed in
	hand; ; condyle; ; fossa; ; zygote; ; trigeminal ganglion; ; otolith organ; ; tail of embryo; ; utricle; ; neural layer of retina; ; genital tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methylated histone binding; protein binding; histone methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity;
Cellular component	MLL1 complex; nucleolus; MLL3/4 complex; nucleus; nucleoplasm; histone methyltransferase complex; Set1C/COMPASS complex;
Biological process	response to estrogen; histone H3-K4 methylation; regulation of transcription, DNA-templated; transcription, DNA-templated; cellular response to DNA damage stimulus; beta-catenin-TCF complex assembly; post-translational protein modification; regulation of megakaryocyte differentiation; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	5929
	213464
	ENSG00000117222
	ENSMUSG00000026439
	Q15291
	Q8BX09
	NM_001193272; NM_001193273; NM_005057
	NM_172517; NM_001357486; NM_001357487
	NP_001180201; NP_001180202; NP_005048
	NP_766105; NP_001344415; NP_001344416
	Wikidata
View/Edit Human	View/Edit Mouse

Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene.