RCAN1

RCAN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WEY
Identifiers
Aliases	RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1, regulator of calcineurin 1
External IDs	OMIM: 602917; MGI: 1890564; HomoloGene: 3251; GeneCards: RCAN1; OMA:RCAN1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	34,615,113 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	92,267,755 bp
RNA expression pattern
	Top expressed in
	optic nerve; ; cartilage tissue; ; C1 segment; ; vena cava; ; epithelium of lactiferous gland; ; lactiferous duct; ; internal globus pallidus; ; glomerulus; ; metanephric glomerulus; ; mucosa of urinary bladder;
	Top expressed in
	epithelium of lens; ; endocardial cushion; ; soleus muscle; ; ankle joint; ; plantaris muscle; ; temporal muscle; ; atrioventricular valve; ; right kidney; ; cardiac muscle tissue of left ventricle; ; vastus lateralis muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; calcium-dependent protein serine/threonine phosphatase regulator activity; identical protein binding; nucleic acid binding;
Cellular component	cytoplasm; nucleus;
Biological process	regulation of calcineurin-NFAT signaling cascade; central nervous system development; calcineurin-NFAT signaling cascade; blood circulation; signal transduction; calcium-mediated signaling; regulation of transcription, DNA-templated; regulation of phosphoprotein phosphatase activity; negative regulation of calcineurin-NFAT signaling cascade;
	Sources:Amigo / QuickGO
Orthologs
	1827
	54720
	ENSG00000159200
	ENSMUSG00000022951
	P53805
	Q9JHG6
NM_001285389; NM_001285391; NM_001285392; NM_001285393; NM_004414;
	NM_203417; NM_203418; NM_001331016
	NM_001081549; NM_019466
NP_001272318; NP_001272320; NP_001272321; NP_001272322; NP_001317945;
	NP_004405; NP_981962; NP_981963
	NP_001075018; NP_062339
	Wikidata
View/Edit Human	View/Edit Mouse

Down syndrome critical region gene 1, also known as DSCR1, is a protein that in humans is encoded by the RCAN1 gene.