RCBTB2

RCBTB2
Identifiers
Aliases	RCBTB2, CHC1L, RLG, RCC1 and BTB domain containing protein 2
External IDs	OMIM: 603524; MGI: 1917200; HomoloGene: 970; GeneCards: RCBTB2; OMA:RCBTB2 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	48,533,256 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	73,445,283 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; monocyte; ; optic nerve; ; parietal pleura; ; visceral pleura; ; Epithelium of choroid plexus; ; retinal pigment epithelium; ; seminal vesicula; ; ganglionic eminence; ; ventricular zone;
	Top expressed in
	otic vesicle; ; saccule; ; otic placode; ; mandibular prominence; ; thymus; ; maxillary prominence; ; somite; ; ventricular zone; ; brown adipose tissue; ; genital tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	acrosomal vesicle; cytoplasmic vesicle;
Biological process	regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	1102
	105670
	ENSG00000136161
	ENSMUSG00000022106
	O95199
	Q99LJ7
NM_001268; NM_001286830; NM_001286831; NM_001286832; NM_001352424;
	NM_001352425; NM_001352426; NM_001352427; NM_001352428; NM_001352429; NM_001352430; NM_001352431
	NM_001170694; NM_134083
NP_001259; NP_001273759; NP_001273760; NP_001273761; NP_001339353;
	NP_001339354; NP_001339355; NP_001339356; NP_001339357; NP_001339358; NP_001339359; NP_001339360
	NP_001164165; NP_598844
	Wikidata
View/Edit Human	View/Edit Mouse

RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene.

This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.