RCE1

RCE1
Identifiers
Aliases	RCE1, FACE2, RCE1A, RCE1B, Ras converting CAAX endopeptidase 1
External IDs	OMIM: 605385; MGI: 1336895; HomoloGene: 3769; GeneCards: RCE1; OMA:RCE1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	66,846,552 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	4,625,641 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; right hemisphere of cerebellum; ; granulocyte; ; right testis; ; left testis; ; skin of abdomen; ; parotid gland; ; gonad; ; anterior pituitary; ; skin of leg;
	Top expressed in
	white adipose tissue; ; proximal tubule; ; right kidney; ; bone marrow; ; yolk sac; ; adrenal gland; ; placenta; ; lip; ; islet of Langerhans; ; Mesencephalon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; cysteine-type endopeptidase activity; endopeptidase activity; metalloendopeptidase activity; hydrolase activity;
Cellular component	integral component of membrane; integral component of endoplasmic reticulum membrane; integral component of plasma membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytosol;
Biological process	proteolysis; CAAX-box protein processing; protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	9986
	19671
	ENSG00000173653
	ENSMUSG00000024889
	Q9Y256
	P57791
	NM_005133; NM_001032279
	NM_023131
	NP_001027450; NP_005124
	NP_075620; NP_001355641; NP_001355642; NP_001355643; NP_001355644
	Wikidata
View/Edit Human	View/Edit Mouse

CAAX prenyl protease 2 is an enzyme that in humans is encoded by the RCE1 gene.

This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins.