RCL1

RCL1
Identifiers
Aliases	RCL1, RNAC, RPCL1, RNA terminal phosphate cyclase like 1
External IDs	OMIM: 611405; MGI: 1913275; HomoloGene: 4217; GeneCards: RCL1; OMA:RCL1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	4,885,917 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	29,121,329 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; right lobe of liver; ; tendon of biceps brachii; ; Achilles tendon; ; tibial arteries; ; body of pancreas; ; cartilage tissue; ; skin of leg; ; skin of abdomen; ; left coronary artery;
	Top expressed in
	left lobe of liver; ; embryo; ; embryo; ; epiblast; ; somite; ; morula; ; morula; ; primitive streak; ; yolk sac; ; fetal liver hematopoietic progenitor cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	catalytic activity; RNA-3'-phosphate cyclase activity; endoribonuclease activity;
Cellular component	nucleus; nucleoplasm; nucleolus;
Biological process	RNA processing; ribosome biogenesis; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); rRNA processing; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); biological process;
	Sources:Amigo / QuickGO
Orthologs
	10171
	59028
	ENSG00000120158
	ENSMUSG00000024785
	Q9Y2P8
	Q9JJT0
	NM_001286699; NM_001286700; NM_001286701; NM_005772
	NM_021525
	NP_001273628; NP_001273629; NP_001273630; NP_005763
	NP_067500
	Wikidata
View/Edit Human	View/Edit Mouse

RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the RCL1 gene.

Copy number variants to the RCL1 gene are associated with a range of neuropsychiatric phenotypes, and a missense variant associated with depression.