Reticulocalbin 1

RCN1
Identifiers
Aliases	RCN1, HEL-S-84, PIG20, RCAL, RCN, reticulocalbin 1
External IDs	OMIM: 602735; MGI: 104559; HomoloGene: 20637; GeneCards: RCN1; OMA:RCN1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	32,105,722 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	105,229,664 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; stromal cell of endometrium; ; ventricular zone; ; cartilage tissue; ; periodontal fiber; ; seminal vesicula; ; tendon of biceps brachii; ; right coronary artery; ; tibia; ; caput epididymis;
	Top expressed in
	seminal vesicula; ; vestibular sensory epithelium; ; gastrula; ; parotid gland; ; umbilical cord; ; dermis; ; utricle; ; atrium; ; human fetus; ; calvaria;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding; metal ion binding;
Cellular component	endoplasmic reticulum lumen; endoplasmic reticulum;
Biological process	post-translational protein modification; in utero embryonic development; camera-type eye development;
	Sources:Amigo / QuickGO
Orthologs
	5954
	19672
	ENSG00000049449
	ENSMUSG00000005973
	Q15293
	Q05186
	NM_002901
	NM_009037
	NP_002892
	NP_033063
	Wikidata
View/Edit Human	View/Edit Mouse

Reticulocalbin-1 is a protein that in humans is encoded by the RCN1 gene.

Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding.