Reticulocalbin 2

RCN2
Identifiers
Aliases	RCN2, E6BP, ERC-55, ERC55, TCBP49, reticulocalbin 2
External IDs	OMIM: 602584; MGI: 1349765; HomoloGene: 2176; GeneCards: RCN2; OMA:RCN2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	76,954,393 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	55,969,166 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; tibia; ; caput epididymis; ; embryo; ; ventricular zone; ; ganglionic eminence; ; cartilage tissue; ; retinal pigment epithelium; ; endometrium; ; tail of epididymis;
	Top expressed in
	saccule; ; otic placode; ; dorsomedial hypothalamic nucleus; ; spermatocyte; ; paraventricular nucleus of hypothalamus; ; mammillary body; ; arcuate nucleus; ; lateral hypothalamus; ; median eminence; ; otic vesicle;
	More reference expression data
	; ;
	More reference expression data
Orthologs
	5955
	26611
	ENSG00000117906
	ENSMUSG00000032320
	Q14257
	Q8BP92
	NM_002902; NM_001271837
	NM_001278274; NM_011992
	NP_001258766; NP_002893
	NP_001265203; NP_036122
	Wikidata
View/Edit Human	View/Edit Mouse

Reticulocalbin-2 is a protein that in humans is encoded by the RCN2 gene.

Reticulocalbin 2 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. The RCN2 gene maps to the same region as type 4 Bardet-Biedl syndrome (MIM:600374), suggesting a possible causative role for reticulocalbin 2 in the disorder.