RDH13

RDH13
Identifiers
Aliases	RDH13, SDR7C3, retinol dehydrogenase 13 (all-trans/9-cis), retinol dehydrogenase 13
External IDs	MGI: 1918732; HomoloGene: 121782; GeneCards: RDH13; OMA:RDH13 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	55,071,291 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,445,649 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; mucosa of transverse colon; ; apex of heart; ; placenta; ; minor salivary glands; ; left ventricle; ; vagina; ; body of stomach; ; right lobe of thyroid gland;
	Top expressed in
	otic vesicle; ; saccule; ; otic placode; ; medullary collecting duct; ; gastric mucosa; ; cardiac muscle tissue of left ventricle; ; superior frontal gyrus; ; mucous cell of stomach; ; epithelium of stomach; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	NADP-retinol dehydrogenase activity; oxidoreductase activity;
Cellular component	mitochondrial inner membrane; mitochondrion; membrane;
Biological process	response to high light intensity; retina layer formation; eye photoreceptor cell development; retinol metabolic process; retinal metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	112724
	108841
ENSG00000278284; ENSG00000274418; ENSG00000276341; ENSG00000275474; ENSG00000274504;
	ENSG00000273944; ENSG00000276684; ENSG00000278149; ENSG00000276826; ENSG00000160439
	ENSMUSG00000008435
	Q8NBN7
	Q8CEE7
	NM_001145971; NM_138412
	NM_001290409; NM_001290411; NM_175372
	NP_001139443; NP_612421
	NP_001277338; NP_001277340; NP_780581
	Wikidata
View/Edit Human	View/Edit Mouse

Retinol dehydrogenase 13 (all-trans/9-cis) is a protein that in humans is encoded by the RDH13 gene. This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described.