RESF1

RESF1
Identifiers
Aliases	RESF1, C12orf35, UTA2-1, GET, retroelement silencing factor 1, KIAA1551
External IDs	MGI: 1914496; HomoloGene: 19251; GeneCards: RESF1; OMA:RESF1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	31,993,107 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	149,237,161 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; lymph node; ; jejunal mucosa; ; blood; ; granulocyte; ; spleen; ; buccal mucosa cell; ; left ovary; ; right ovary; ; monocyte;
	Top expressed in
	zygote; ; cumulus cell; ; secondary oocyte; ; Rostral migratory stream; ; tail of embryo; ; primary oocyte; ; genital tubercle; ; blood; ; internal carotid artery; ; external carotid artery;
	More reference expression data
	n/a
Gene ontology
Molecular function	histone binding;
Cellular component	gamma-tubulin complex; nucleus;
Biological process	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; positive regulation of DNA methylation-dependent heterochromatin assembly;
	Sources:Amigo / QuickGO
Orthologs
	55196
	67246
	ENSG00000174718
	ENSMUSG00000032712
	Q9HCM1
	Q5DTW7
	NM_018169
	NM_001289661; NM_001289662; NM_026054
	NP_060639
	NP_001276590; NP_001276591; NP_080330
	Wikidata
View/Edit Human	View/Edit Mouse

Retroelement silencing factor 1 is a protein that in humans is encoded by the RESF1 gene. RESF1 is broadly expressed in the lymph nodes, ovaries, appendix and spleen. RESF1 shows characteristics of being a minor histocompatibility antigen, as well as tumor suppressor capabilities. The high expression in the lymph nodes and spleen indicate function in the immune system.