Repulsive guidance molecule B

RGMB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4BQ6, 4BQ7, 4BQ8, 4UHZ, 4UI0, 4UI2
Identifiers
Aliases	RGMB, DRAGON, repulsive guidance molecule family member b, repulsive guidance molecule BMP co-receptor b
External IDs	OMIM: 612687; MGI: 1916049; HomoloGene: 65355; GeneCards: RGMB; OMA:RGMB - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	98,798,643 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	15,831,039 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; pylorus; ; skin of arm; ; skin of thigh; ; tibialis anterior muscle; ; cardia; ; cardiac muscle tissue of right atrium; ; rectum; ; deltoid muscle; ; spinal ganglia;
	Top expressed in
	Rostral migratory stream; ; otolith organ; ; utricle; ; Paneth cell; ; lateral habenular nucleus; ; paraventricular nucleus of thalamus; ; medial habenular nucleus; ; spinal ganglia; ; lumbar spinal ganglion; ; sciatic nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	coreceptor activity; identical protein binding; protein binding;
Cellular component	membrane raft; anchored component of membrane; plasma membrane; membrane; endoplasmic reticulum-Golgi intermediate compartment; anchored component of plasma membrane;
Biological process	positive regulation of transcription, DNA-templated; signal transduction; BMP signaling pathway; cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	285704
	68799
	ENSG00000174136
	ENSMUSG00000048027
	Q6NW40
	Q7TQ33
NM_001012761; NM_173670; NM_001366508; NM_001366509; NM_001366510;
	NM_001366511
	NM_178615
	NP_001012779; NP_001353437; NP_001353438; NP_001353439; NP_001353440
	NP_848730
	Wikidata
View/Edit Human	View/Edit Mouse

Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. In humans this protein is encoded by the RGMB gene.