Retinal G protein coupled receptor

RGR
Identifiers
Aliases	RGR, RP44, Retinal G protein coupled receptor
External IDs	OMIM: 600342; MGI: 1929473; HomoloGene: 37709; GeneCards: RGR; OMA:RGR - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	84,259,960 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	36,770,921 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; gastric mucosa; ; testicle; ; cingulate gyrus; ; anterior cingulate cortex; ; nucleus accumbens; ; caudate nucleus; ; right frontal lobe; ; gonad; ; Brodmann area 9;
	Top expressed in
	retinal pigment epithelium; ; choroid; ; olfactory epithelium; ; ciliary body; ; epithelium of lens; ; lacrimal gland; ; iris; ; neural layer of retina; ; corneal stroma; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; protein binding; photoreceptor activity; signal transducer activity; G protein-coupled photoreceptor activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction; visual perception; response to stimulus; phototransduction; detection of visible light; cellular response to light stimulus;
	Sources:Amigo / QuickGO
Orthologs
	5995
	57811
	ENSG00000148604
	ENSMUSG00000021804
	P47804
	Q9Z2B3
	NM_001012720; NM_001012722; NM_002921
	NM_001301692; NM_001301694; NM_021340
	NP_001012738; NP_001012740; NP_002912
	NP_001288621; NP_001288623; NP_067315
	Wikidata
View/Edit Human	View/Edit Mouse

RPE-retinal G protein-coupled receptor also known as RGR-opsin is a protein that in humans is encoded by the RGR gene. RGR-opsin is a member of the rhodopsin-like receptor subfamily of GPCR. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. RGR-opsin comes in different isoforms produced by alternative splicing.