RGS19

RGS19
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CMZ
Identifiers
Aliases	RGS19, GAIP, RGSGAIP, regulator of G-protein signaling 19, regulator of G protein signaling 19
External IDs	OMIM: 605071; MGI: 1915153; HomoloGene: 23320; GeneCards: RGS19; OMA:RGS19 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	64,079,988 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	181,335,770 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; monocyte; ; spleen; ; bone marrow cells; ; parotid gland; ; trabecular bone; ; lymph node; ; amniotic fluid; ; appendix;
	Top expressed in
	granulocyte; ; mesenteric lymph nodes; ; external carotid artery; ; spleen; ; blood; ; thymus; ; internal carotid artery; ; yolk sac; ; condyle; ; tibiofemoral joint;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	GTPase activator activity; protein binding; G-protein alpha-subunit binding; GTPase activity;
Cellular component	cytoplasm; Golgi apparatus; membrane; brush border; heterotrimeric G-protein complex; membrane raft; clathrin-coated vesicle; cytoplasmic vesicle; plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; small GTPase mediated signal transduction; autophagy; negative regulation of signal transduction; positive regulation of GTPase activity; response to ethanol;
	Sources:Amigo / QuickGO
Orthologs
	10287
	56470
	ENSG00000171700
	ENSMUSG00000002458
	P49795
	Q9CX84
	NM_001039467; NM_005873
NM_001291205; NM_001291206; NM_001291207; NM_001291208; NM_001291209;
	NM_001291210; NM_026446
	NP_001034556; NP_005864
NP_001278134; NP_001278135; NP_001278136; NP_001278137; NP_001278138;
	NP_001278139; NP_080722
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of G-protein signaling 19 is a protein that in humans is encoded by the RGS19 gene.

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling.