RGS4

RGS4
Identifiers
Aliases	RGS4, Rgs4, AA004315, AA597169, ESTM48, ESTM50, RGP4, SCZD9, regulator of G-protein signaling 4, regulator of G protein signaling 4
External IDs	OMIM: 602516; MGI: 108409; HomoloGene: 4100; GeneCards: RGS4; OMA:RGS4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	163,076,802 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	169,575,211 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; endothelial cell; ; frontal pole; ; orbitofrontal cortex; ; superior frontal gyrus; ; Brodmann area 46; ; primary visual cortex; ; prefrontal cortex; ; parietal lobe;
	Top expressed in
	superior cervical ganglion; ; facial motor nucleus; ; prefrontal cortex; ; superior frontal gyrus; ; lateral geniculate nucleus; ; spinal ganglia; ; medial dorsal nucleus; ; olfactory tubercle; ; pontine nuclei; ; mammillary body;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	G-protein alpha-subunit binding; calmodulin binding; GTPase activator activity; GTPase activity;
Cellular component	cytoplasm; cytosol; plasma membrane; membrane; nucleus; protein-containing complex;
Biological process	positive regulation of GTPase activity; negative regulation of signal transduction; negative regulation of G protein-coupled receptor signaling pathway; regulation of G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway; response to amphetamine; brain development; positive regulation of heart rate; response to cocaine; response to morphine; response to ethanol; regulation of calcium ion transport; negative regulation of dopamine receptor signaling pathway; negative regulation of cell growth involved in cardiac muscle cell development; regulation of actin filament organization; negative regulation of glycine import across plasma membrane; regulation of potassium ion transmembrane transport; negative regulation of potassium ion transmembrane transport; dorsal root ganglion development; positive regulation of excitatory postsynaptic potential;
	Sources:Amigo / QuickGO
Orthologs
	5999
	19736
	ENSG00000117152
	ENSMUSG00000038530
	P49798
	O08899
	NM_001102445; NM_001113380; NM_001113381; NM_005613
	NM_009062
	NP_001095915; NP_001106851; NP_001106852; NP_005604; NP_005604.1
	NP_033088
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of G protein signaling 4 also known as RGP4 is a protein that in humans is encoded by the RGS4 gene. RGP4 regulates G protein signaling.