RGS6

RGS6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ES0
Identifiers
Aliases	RGS6, GAP, regulator of G-protein signaling 6, regulator of G protein signaling 6, HA117, S914
External IDs	OMIM: 603894; MGI: 1354730; HomoloGene: 68385; GeneCards: RGS6; OMA:RGS6 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	72,566,529 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	83,208,830 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; middle temporal gyrus; ; Achilles tendon; ; prefrontal cortex; ; testicle; ; right frontal lobe; ; primary visual cortex; ; Brodmann area 23; ; apex of heart; ; buccal mucosa cell;
	Top expressed in
	facial motor nucleus; ; superior frontal gyrus; ; neural layer of retina; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; aortic valve; ; atrium; ; embryo; ; right kidney;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; GTPase activator activity; GTPase activity;
Cellular component	cytosol; plasma membrane; membrane; nucleus; extrinsic component of membrane; cytoplasm; intracellular anatomical structure;
Biological process	G protein-coupled receptor signaling pathway; positive regulation of GTPase activity; negative regulation of signal transduction; intracellular signal transduction; regulation of G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9628
	50779
	ENSG00000182732
	ENSMUSG00000021219
	P49758
	Q9Z2H2
NM_001204416; NM_001204417; NM_001204418; NM_001204419; NM_001204420;
	NM_001204421; NM_001204422; NM_001204423; NM_001204424; NM_004296
	NM_001282061; NM_015812; NM_001310478
NP_001191345; NP_001191346; NP_001191347; NP_001191348; NP_001191349;
	NP_001191350; NP_001191351; NP_001191352; NP_001191353; NP_004287; NP_001357199; NP_001357200; NP_001357201; NP_001357202; NP_001357203; NP_001357204; NP_001357205; NP_001357206; NP_001357207; NP_001357208; NP_001357209; NP_001357210; NP_001357211; NP_001357212; NP_001357213; NP_001357215; NP_001357216; NP_001357217; NP_001357218; NP_001357219; NP_001357220; NP_001357221; NP_001357222; NP_001357223
	NP_001268990; NP_001297407; NP_056627
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene.

Members of the Regulator of G protein signaling (RGS) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the guanine nucleotide-binding G alpha subunit.[supplied by OMIM]