RHOB

RHOB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2FV8
Identifiers
Aliases	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6, ras homolog family member B
External IDs	OMIM: 165370; MGI: 107949; HomoloGene: 68377; GeneCards: RHOB; OMA:RHOB - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	20,449,440 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	8,550,009 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; saphenous vein; ; popliteal artery; ; tibial arteries; ; vena cava; ; urethra; ; internal globus pallidus; ; nipple; ; left uterine tube; ; tail of epididymis;
	Top expressed in
	molar; ; decidua; ; granulocyte; ; dorsomedial hypothalamic nucleus; ; left lung lobe; ; olfactory tubercle; ; globus pallidus; ; lateral geniculate nucleus; ; stroma of bone marrow; ; subiculum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; GTP binding; protein binding; GTPase activity; protein kinase binding;
Cellular component	cytosol; endosome; late endosome; membrane; late endosome membrane; focal adhesion; plasma membrane; early endosome; cleavage furrow; endosome membrane; extracellular exosome; nucleus; intracellular anatomical structure; cytoplasm; cell cortex; cell division site; intracellular membrane-bounded organelle;
Biological process	cell differentiation; regulation of cell migration; endosome to lysosome transport; endothelial tube morphogenesis; negative regulation of cell cycle; positive regulation of angiogenesis; positive regulation of endothelial cell migration; multicellular organism development; platelet activation; cell adhesion; negative regulation of cell migration; angiogenesis; Rho protein signal transduction; cellular response to ionizing radiation; protein transport; intracellular protein transport; regulation of small GTPase mediated signal transduction; cellular response to hydrogen peroxide; apoptotic process; small GTPase mediated signal transduction; positive regulation of apoptotic process; transport; mitotic cytokinesis; G protein-coupled receptor signaling pathway; actin filament organization; regulation of cell shape; cell migration; establishment or maintenance of actin cytoskeleton polarity; regulation of actin cytoskeleton organization; actin filament bundle assembly;
	Sources:Amigo / QuickGO
Orthologs
	388
	11852
	ENSG00000143878
	ENSMUSG00000054364
	P62745
	P62746
	NM_004040
	NM_007483
	NP_004031
	NP_031509
	Wikidata
View/Edit Human	View/Edit Mouse

Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.

RHOB is a member of the Rho GTP-binding protein family.