RhoG

RHOG
Identifiers
Aliases	RHOG, ARHG, RhoG, ras homolog family member G
External IDs	OMIM: 179505; MGI: 1928370; HomoloGene: 68196; GeneCards: RHOG; OMA:RHOG - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	3,840,959 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	101,905,261 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; monocyte; ; spleen; ; C1 segment; ; bone marrow; ; lymph node; ; olfactory bulb; ; bone marrow cells; ; right lung;
	Top expressed in
	granulocyte; ; tibiofemoral joint; ; lip; ; bone marrow; ; stroma of bone marrow; ; thymus; ; yolk sac; ; blood; ; spleen; ; pyloric antrum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; protein kinase binding; phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
Cellular component	cytosol; endoplasmic reticulum membrane; membrane; focal adhesion; plasma membrane; extracellular exosome; secretory granule membrane; intracellular anatomical structure; cytoplasm; cell cortex; cell projection;
Biological process	activation of GTPase activity; platelet activation; positive regulation of transcription, DNA-templated; Rho protein signal transduction; positive regulation of cell population proliferation; regulation of ruffle assembly; cell chemotaxis; Rac protein signal transduction; regulation of small GTPase mediated signal transduction; actin cytoskeleton organization; small GTPase mediated signal transduction; neutrophil degranulation; positive regulation of protein localization to plasma membrane; G protein-coupled receptor signaling pathway; actin filament organization; establishment or maintenance of cell polarity; regulation of cell shape; regulation of actin cytoskeleton organization; phosphatidylinositol phosphate biosynthetic process; positive regulation of protein kinase B signaling;
	Sources:Amigo / QuickGO
Orthologs
	391
	56212
	ENSG00000177105
	ENSMUSG00000073982
	P84095
	P84096
	NM_001665
	NM_019566
	NP_001656
	NP_062512
	Wikidata
View/Edit Human	View/Edit Mouse

RhoG (Ras homology Growth-related) (or ARGH) is a small (~21 kDa) monomeric GTP-binding protein (G protein), and is an important component of many intracellular signalling pathways. It is a member of the Rac subfamily of the Rho family of small G proteins and is encoded by the gene RHOG.