RIMS2

RIMS2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1V27, 1WFG
Identifiers
Aliases	RIMS2, OBOE, RAB3IP3, RIM2, regulating synaptic membrane exocytosis 2
External IDs	OMIM: 606630; MGI: 2152972; HomoloGene: 81639; GeneCards: RIMS2; OMA:RIMS2 - orthologs
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	39,547,768 bp
RNA expression pattern
	n/a
	Top expressed in
	Rostral migratory stream; ; neural layer of retina; ; lateral geniculate nucleus; ; medial dorsal nucleus; ; cerebellar vermis; ; lobe of cerebellum; ; inferior colliculi; ; nucleus accumbens; ; lateral septal nucleus; ; medial geniculate nucleus;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; transmembrane transporter binding;
Cellular component	membrane; plasma membrane; synapse; intracellular anatomical structure; presynaptic active zone; cell junction; extracellular exosome; presynaptic membrane; cytoskeleton of presynaptic active zone; presynaptic active zone cytoplasmic component;
Biological process	cell differentiation; spontaneous neurotransmitter secretion; positive regulation of inhibitory postsynaptic potential; insulin secretion; regulation of exocytosis; positive regulation of gene expression; positive regulation of excitatory postsynaptic potential; positive regulation of dendrite extension; intracellular protein transport; cAMP-mediated signaling; calcium-ion regulated exocytosis; regulation of membrane potential; calcium ion-regulated exocytosis of neurotransmitter; regulation of synaptic vesicle exocytosis; exocytosis; regulation of synaptic plasticity; positive regulation of synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	9699
	116838
	ENSG00000176406
	ENSMUSG00000037386
	Q9UQ26
	Q9EQZ7
	NM_001100117; NM_001282881; NM_001282882; NM_014677
	NM_001256382; NM_001256383; NM_001256384; NM_053271
NP_001093587; NP_001269810; NP_001269811; NP_055492; NP_001335413;
	NP_001335414; NP_001335415; NP_001335416; NP_001335417; NP_001335418; NP_001335419; NP_001335420; NP_001335421; NP_001335422; NP_001335423; NP_001335424; NP_001335425; NP_001335426; NP_001335427; NP_001335428; NP_001335429; NP_001335430; NP_001335431; NP_001335432; NP_001335433; NP_001335434; NP_001335435; NP_001335436; NP_001335437; NP_001335438
	NP_001243311; NP_001243312; NP_001243313; NP_444501
	Wikidata
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Regulating synaptic membrane exocytosis protein 2 is a protein that in humans is encoded by the RIMS2 gene.