RJR-2429

RJR-2429
Identifiers
CAS Number	91556-75-1;
PubChem CID	10176454;
ChemSpider	8351959;
UNII	Q2L6T24QLT;
CompTox Dashboard (EPA)	DTXSID40436425 ;
Chemical and physical data
Formula	C12H16N2
Molar mass	188.274 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(C2N(CC3)CCC3C2)=CN=CC=C1;
	InChI InChI=1S/C12H16N2/c1-2-11(9-13-5-1)12-8-10-3-6-14(12)7-4-10/h1-2,5,9-10,12H,3-4,6-8H2; Key:YJYPZLAZNIGNRP-UHFFFAOYSA-N;

RJR-2429 is a drug that acts as an agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. RJR-2429 is stronger than nicotine but weaker than epibatidine in most assays, and with high affinity for both α3β4 and α4β2 subtypes, as well as the less studied α1βγδ subtype.

Identifiers

CAS Number	91556-75-1
PubChem CID	10176454
ChemSpider	8351959
UNII	Q2L6T24QLT
CompTox Dashboard (EPA)	DTXSID40436425
Chemical and physical data
Formula	C₁₂H₁₆N₂
Molar mass	188.274 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1(C2N(CC3)CCC3C2)=CN=CC=C1
InChI InChI=1S/C12H16N2/c1-2-11(9-13-5-1)12-8-10-3-6-14(12)7-4-10/h1-2,5,9-10,12H,3-4,6-8H2 Key:YJYPZLAZNIGNRP-UHFFFAOYSA-N