RMDN3

RMDN3
Identifiers
Aliases	RMDN3, FAM82A2, FAM82C, RMD-3, RMD3, ptpip51, regulator of microtubule dynamics 3
External IDs	OMIM: 611873; MGI: 1915059; HomoloGene: 34926; GeneCards: RMDN3; OMA:RMDN3 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	40,755,851 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	118,987,515 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; C1 segment; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; jejunal mucosa; ; anterior cingulate cortex; ; prefrontal cortex; ; right frontal lobe; ; Amygdala; ; duodenum;
	Top expressed in
	retinal pigment epithelium; ; lobe of cerebellum; ; seminal vesicula; ; cerebellar vermis; ; jejunum; ; neural layer of retina; ; olfactory epithelium; ; mucous cell of stomach; ; brown adipose tissue; ; dorsal tegmental nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; integral component of membrane; mitochondrial outer membrane; spindle; spindle pole; microtubule; cytoskeleton; membrane; mitochondrion; nucleus; mitochondrial membranes;
Biological process	cell differentiation; cellular calcium ion homeostasis; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	55177
	67809
	ENSG00000137824
	ENSMUSG00000070730
	Q96TC7
	Q3UJU9
NM_001304802; NM_018145; NM_001323894; NM_001323895; NM_001323896;
	NM_001323897
	NM_001033136
NP_001291731; NP_001310823; NP_001310824; NP_001310825; NP_001310826;
	NP_060615
	NP_001028308
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of microtubule dynamics protein 3 (RMDN3), more commonly known as Protein tyrosine phosphatase interacting protein 51 (PTPIP51), is a protein that in humans is encoded by the RMDN3 gene on chromosome 15. This protein contributes to multiple biological functions, including cellular differentiation, proliferation, motility, cytoskeleton formation, and apoptosis, and has been associated with numerous cancers.