RNF111

RNF111
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KIZ
Identifiers
Aliases	RNF111, ARK, ring finger protein 111, hRNF111
External IDs	OMIM: 605840; MGI: 1934919; HomoloGene: 9741; GeneCards: RNF111; OMA:RNF111 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	59,097,419 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	70,411,007 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; monocyte; ; ganglionic eminence; ; Epithelium of choroid plexus; ; ventricular zone; ; epithelium of colon; ; stromal cell of endometrium; ; tonsil; ; sural nerve;
	Top expressed in
	zygote; ; cumulus cell; ; secondary oocyte; ; granulocyte; ; primitive streak; ; blood; ; parotid gland; ; pineal gland; ; lymph node; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SUMO polymer binding; protein binding; metal ion binding; ubiquitin protein ligase activity; transferase activity; SMAD binding;
Cellular component	nucleoplasm; nucleus; cytoplasm; cytosol; PML body; protein-containing complex;
Biological process	positive regulation of transcription, DNA-templated; ubiquitin-dependent SMAD protein catabolic process; protein polyubiquitination; multicellular organism development; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of protein ubiquitination; pattern specification process; proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination; global genome nucleotide-excision repair; positive regulation of transcription by RNA polymerase II; DNA repair; cellular response to DNA damage stimulus; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	54778
	93836
	ENSG00000157450
	ENSMUSG00000032217
	Q6ZNA4
	Q99ML9
	NM_001270528; NM_001270529; NM_001270530; NM_017610; NM_001330331
	NM_033604; NM_001357494; NM_001374753
	NP_001257457; NP_001257458; NP_001257459; NP_001317260; NP_060080
	NP_291082; NP_001344423; NP_001361682
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase Arkadia is an enzyme that in humans is encoded by the RNF111 gene.