RNF113A

RNF113A
Identifiers
Aliases	RNF113A, Cwc24, RNF113, ZNF183, TTD5, ring finger protein 113A
External IDs	OMIM: 300951; MGI: 1913631; HomoloGene: 133824; GeneCards: RNF113A; OMA:RNF113A - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	119,871,733 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	84,465,352 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; tendon of biceps brachii; ; parotid gland; ; blood; ; spleen; ; body of pancreas; ; mucosa of transverse colon; ; testicle; ; olfactory zone of nasal mucosa;
	Top expressed in
	zygote; ; secondary oocyte; ; interventricular septum; ; neural layer of retina; ; spermatid; ; supraoptic nucleus; ; granulocyte; ; Paneth cell; ; primary oocyte; ; otic vesicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; ubiquitin-protein transferase activity; transferase activity;
Cellular component	U2-type spliceosomal complex; nucleus; spliceosomal complex; nuclear speck; U2-type precatalytic spliceosome;
Biological process	mRNA cis splicing, via spliceosome; snoRNA splicing; protein ubiquitination; isopeptide cross-linking via N6-glycyl-L-lysine; negative regulation of chemokine-mediated signaling pathway; DNA repair; mRNA processing; cellular response to DNA damage stimulus; RNA splicing; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	7737
	66381
	ENSG00000125352
	ENSMUSG00000098134
	O15541
	n/a
	NM_006978
	NM_025525
	NP_008909
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Ring Finger Protein 113A is a protein that in humans is encoded by the RNF113A gene. It is found in humans on the X Chromosome. RNF113A contains two highly conserved domains, the RING (Really Interesting New Gene) finger domain and Zinc finger domain. RING finger domains have been associated with some tumor suppressors and cytokine receptor-associated molecules. These domains also act in DNA repair and mediating protein-protein interactions. Aliases of RNF113A across taxa include RNF113, CWC24, and ZNF183.