RNF213

RNF213
Identifiers
Aliases	RNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57, ring finger protein 213
External IDs	OMIM: 613768; MGI: 1289196; HomoloGene: 45439; GeneCards: RNF213; OMA:RNF213 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	80,398,794 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	119,378,244 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; pancreatic ductal cell; ; spleen; ; sural nerve; ; bone marrow cells; ; upper lobe of left lung; ; monocyte; ; right lobe of thyroid gland; ; right uterine tube; ; gastric mucosa;
	Top expressed in
	cervix; ; lymph node; ; epithelium of small intestine; ; stroma of bone marrow; ; mesenteric lymph nodes; ; ovary; ; otolith organ; ; utricle; ; interventricular septum; ; submandibular gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; metal ion binding; hydrolase activity; ATPase activity; ubiquitin-protein transferase activity; transferase activity;
Cellular component	nucleolus; membrane; cytoplasm; cytosol;
Biological process	ubiquitin-dependent protein catabolic process; negative regulation of non-canonical Wnt signaling pathway; angiogenesis; sprouting angiogenesis; protein homooligomerization; protein autoubiquitination; protein ubiquitination; protein polyubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	57674
	672511
	ENSG00000173821
	ENSMUSG00000070327
	Q63HN8
	n/a
	NM_001256071; NM_020914; NM_020954
	NM_001040005
	NP_001243000; NP_066005
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Ring finger protein 213 is a protein that in humans is encoded by the RNF213 gene. RNF213 is a 591kDa cytosolic E3 ubiquitin ligase with RING finger and AAA+ ATPase domains.