RNF40

RNF40
Identifiers
Aliases	RNF40, BRE1B, RBP95, STARING, ring finger protein 40
External IDs	OMIM: 607700; MGI: 2142048; HomoloGene: 8856; GeneCards: RNF40; OMA:RNF40 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,776,307 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,203,971 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; left testis; ; right testis; ; ganglionic eminence; ; mucosa of transverse colon; ; islet of Langerhans; ; right lobe of thyroid gland; ; granulocyte; ; sural nerve; ; right hemisphere of cerebellum;
	Top expressed in
	granulocyte; ; spermatid; ; spermatocyte; ; neural layer of retina; ; zygote; ; ventricular zone; ; lip; ; muscle of thigh; ; dentate gyrus of hippocampal formation granule cell; ; esophagus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein-containing complex binding; ubiquitin conjugating enzyme binding; syntaxin-1 binding; protein homodimerization activity; mRNA 3'-UTR binding; ubiquitin protein ligase binding; protein binding; ubiquitin-protein transferase activity; transferase activity;
Cellular component	axon terminus; cytosol; membrane; HULC complex; extrinsic component of membrane; ubiquitin ligase complex; nucleus; neuron projection; nucleoplasm; protein-containing complex;
Biological process	negative regulation of mRNA polyadenylation; histone H2B ubiquitination; positive regulation of proteasomal protein catabolic process; response to peptide hormone; regulation of mitotic cell cycle; positive regulation of protein polyubiquitination; histone monoubiquitination; ubiquitin-dependent protein catabolic process; positive regulation of histone H2B ubiquitination; protein ubiquitination; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	9810
	233900
	ENSG00000103549
	ENSMUSG00000030816
	O75150
	Q3U319
	NM_001207033; NM_001207034; NM_001286572; NM_014771; NM_194352
	NM_172281; NM_001360883
	NP_001193962; NP_001193963; NP_001273501; NP_055586
	NP_758485; NP_001347812
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase BRE1B is an enzyme that in humans is encoded by the RNF40 gene.