RNF41

RNF41
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2FZP, 2GWF
Identifiers
Aliases	RNF41, FLRF, NRDP1, SBBI03, ring finger protein 41
External IDs	MGI: 1914838; HomoloGene: 4226; GeneCards: RNF41; OMA:RNF41 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	56,221,933 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,277,310 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; paraflocculus of cerebellum; ; frontal pole; ; islet of Langerhans; ; monocyte; ; lateral nuclear group of thalamus; ; stromal cell of endometrium; ; gallbladder; ; right coronary artery; ; popliteal artery;
	Top expressed in
	seminiferous tubule; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; spermatid; ; superior frontal gyrus; ; ventricular zone; ; granulocyte; ; ganglionic eminence; ; Rostral migratory stream; ; cerebellar cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	interleukin-3 receptor binding; erythropoietin receptor binding; zinc ion binding; metal ion binding; protein binding; transferase activity; ubiquitin-protein transferase activity; protein domain specific binding; receptor tyrosine kinase binding; ubiquitin protein ligase activity;
Cellular component	cytosol; perinuclear region of cytoplasm; endoplasmic reticulum tubular network;
Biological process	regulation of MAPK cascade; extrinsic apoptotic signaling pathway; positive regulation of DNA-binding transcription factor activity; protein polyubiquitination; regulation of reactive oxygen species metabolic process; autophagy; negative regulation of cell migration; regulation of lymphocyte differentiation; positive regulation of reactive oxygen species metabolic process; protein ubiquitination; regulation of protein kinase B signaling; regulation of gene expression; proteasomal protein catabolic process; regulation of myeloid cell differentiation; regulation of establishment of cell polarity; negative regulation of cell population proliferation; protein autoubiquitination; apoptotic process; negative regulation of mitophagy; positive regulation of protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10193
	67588
	ENSG00000181852
	ENSMUSG00000025373
	Q9H4P4
	Q8BH75
	NM_001242826; NM_005785; NM_194358; NM_194359
	NM_001164237; NM_026259
	NP_001229755; NP_005776; NP_919339; NP_919340
	NP_001157709; NP_080535
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase NRDP1 is an enzyme that in humans is encoded by the RNF41 gene.