RNF5

RNF5
Identifiers
Aliases	RNF5, RING5, RMA1, ring finger protein 5
External IDs	OMIM: 602677; MGI: 1860076; HomoloGene: 56004; GeneCards: RNF5; OMA:RNF5 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	32,180,793 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,822,664 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; human kidney; ; ventricular zone; ; right adrenal gland; ; mucosa of transverse colon; ; right adrenal cortex; ; monocyte; ; apex of heart; ; left ventricle; ; duodenum;
	Top expressed in
	proximal tubule; ; right kidney; ; neural tube; ; neural layer of retina; ; yolk sac; ; ganglionic eminence; ; human kidney; ; Pons; ; brown adipose tissue; ; olfactory bulb;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; ubiquitin-protein transferase activity; protein binding; ubiquitin-like protein conjugating enzyme binding; transferase activity; identical protein binding; zinc ion binding; ubiquitin protein ligase activity; protein-containing complex binding;
Cellular component	integral component of membrane; mitochondrial membranes; membrane; mitochondrion; Derlin-1 retrotranslocation complex; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment;
Biological process	response to bacterium; protein K63-linked ubiquitination; ER-associated misfolded protein catabolic process; regulation of autophagosome assembly; protein K48-linked ubiquitination; protein destabilization; protein ubiquitination; negative regulation of autophagy; transmembrane transport; endoplasmic reticulum mannose trimming; ubiquitin-dependent ERAD pathway; ERAD pathway; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	6048
	54197
ENSG00000227277; ENSG00000223767; ENSG00000228907; ENSG00000183574; ENSG00000204308;
	ENSG00000225452; ENSG00000228405
	ENSMUSG00000015478
	Q99942
	O35445
	NM_006913
	NM_019403
	NP_008844
	NP_062276
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase RNF5 is an enzyme that in humans is encoded by the RNF5 gene.