60S ribosomal protein L17

RPL17
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5AJ0, 4V5Z, 4UJD, 5A8L, 4D67, 3J92, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL17, L17, PD-1, RPL23, ribosomal protein L17
External IDs	OMIM: 603661; MGI: 2448270; HomoloGene: 115574; GeneCards: RPL17; OMA:RPL17 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	49,492,523 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	75,136,452 bp
RNA expression pattern
	Top expressed in
	left ovary; ; right ovary; ; right uterine tube; ; endometrium; ; anterior pituitary; ; body of uterus; ; Achilles tendon; ; left lobe of thyroid gland; ; body of pancreas; ; canal of the cervix;
	Top expressed in
	uterus; ; ventricular zone; ; epiblast; ; spleen; ; thymus; ; ganglionic eminence; ; lens; ; zone of skin; ; pancreas; ; bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; structural constituent of ribosome; RNA binding;
Cellular component	cytosol; ribosome; large ribosomal subunit; intracellular anatomical structure; cytosolic large ribosomal subunit; nucleus;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; rRNA processing; protein biosynthesis; cytoplasmic translation;
	Sources:Amigo / QuickGO
Orthologs
	6139
	319195
	ENSG00000265681
	ENSMUSG00000062328
	P18621
	Q9CPR4; Q6ZWZ7
NM_001199345; NM_000985; NM_001035006; NM_001199340; NM_001199341;
	NM_001199342; NM_001199343; NM_001199344
	NM_001002239
NP_000976; NP_001030178; NP_001186269; NP_001186270; NP_001186271;
	NP_001186272; NP_001186273; NP_001186274; NP_001356484; NP_001356485; NP_001356486; NP_001356487; NP_001356489; NP_001356490; NP_001356491; NP_001356492
	NP_001002239; NP_001392893; NP_001392894; NP_001392895
	Wikidata
View/Edit Human	View/Edit Mouse

Large ribosomal subunit protein uL22 is a protein that in humans is encoded by the RPL17 gene.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as RPL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Haloarcula marismortui; however, its official symbol is RPL17. Two alternative splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.