40S ribosomal protein S11

RPS11
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0, 4KZY, 3J7R, 4D61, 4KZX, 4D5L, 4V5Z, 5FLX, 4UJD, 3J7P, 4KZZ, 4UJE, 4UJC
Identifiers
Aliases	RPS11, S11, ribosomal protein S11
External IDs	OMIM: 180471; MGI: 1351329; HomoloGene: 88443; GeneCards: RPS11; OMA:RPS11 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,499,708 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,773,863 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; ganglionic eminence; ; skin of hip; ; skin of arm; ; urethra; ; human penis; ; mucosa of sigmoid colon; ; beta cell; ; superficial temporal artery; ; nipple;
	Top expressed in
	epiblast; ; embryo; ; ventricular zone; ; embryo; ; ganglionic eminence; ; blastocyst; ; thymus; ; morula; ; zone of skin; ; ileum;
	More reference expression data
	n/a
Gene ontology
Molecular function	rRNA binding; structural constituent of ribosome; protein binding; RNA binding;
Cellular component	cytoplasm; cytosol; ribosome; focal adhesion; intracellular anatomical structure; nucleolus; extracellular exosome; nucleoplasm; extracellular matrix; membrane; cytosolic small ribosomal subunit;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; protein biosynthesis; rRNA processing; osteoblast differentiation;
	Sources:Amigo / QuickGO
Orthologs
	6205
	27207
	ENSG00000142534
	ENSMUSG00000003429
	P62280
	P62281
	NM_001015
	NM_013725
	NP_001006
	NP_038753
	Wikidata
View/Edit Human	View/Edit Mouse

40S ribosomal protein S11 is a protein that in humans is encoded by the RPS11 gene.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.