RPS6KA3

RPS6KA3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4D9T, 4D9U, 4JG6, 4JG7, 4JG8, 4NUS, 4NW5, 4NW6, 5D9K, 5D9L
Identifiers
Aliases	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2, ribosomal protein S6 kinase A3, XLID19
External IDs	OMIM: 300075; MGI: 104557; HomoloGene: 37940; GeneCards: RPS6KA3; OMA:RPS6KA3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	20,267,519 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	158,151,240 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; mucosa of sigmoid colon; ; biceps brachii; ; triceps brachii muscle; ; islet of Langerhans; ; deltoid muscle; ; gastrocnemius muscle; ; glutes; ; quadriceps femoris muscle; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	trigeminal ganglion; ; body of femur; ; left colon; ; white adipose tissue; ; lumbar spinal ganglion; ; Paneth cell; ; left lung lobe; ; genital tubercle; ; mandibular prominence; ; gastrula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; metal ion binding; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein binding; ATP binding; protein kinase binding; magnesium ion binding; kinase activity; protein serine/threonine kinase activity; ribosomal protein S6 kinase activity;
Cellular component	cytoplasm; cytosol; nucleoplasm; nucleus;
Biological process	skeletal system development; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of translation in response to stress; intracellular signal transduction; phosphorylation; negative regulation of apoptotic process; protein phosphorylation; central nervous system development; positive regulation of cell growth; response to lipopolysaccharide; positive regulation of cell differentiation; cell cycle; regulation of DNA-templated transcription in response to stress; signal transduction; positive regulation of transcription by RNA polymerase II; toll-like receptor signaling pathway; apoptotic process; peptidyl-serine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	6197
	110651
	ENSG00000177189
	ENSMUSG00000031309
	P51812
	P18654
	NM_004586
	NM_148945; NM_001346675
	NP_004577
	NP_001333604; NP_683747
	Wikidata
View/Edit Human	View/Edit Mouse

protein S6 kinase, 90kDa, polypeptide 3, also s RPS6KA3, is an enzyme that in humans is encoded by the RPS6KA3 gene.