Ribosomal protein SA

RPSA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3BCH, 4UG0, 4V6X, 5A2Q, 5AJ0, 4UJE, 4D5L, 4UJD, 5FLX, 4D61
Identifiers
Aliases	RPSA, 37LRP, 67LR, ICAS, LAMBR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, NEM/1CHD4, SA, lamR, p40, Ribosomal protein SA
External IDs	OMIM: 150370; MGI: 105381; HomoloGene: 68249; GeneCards: RPSA; OMA:RPSA - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	39,412,542 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	119,961,435 bp
RNA expression pattern
	Top expressed in
	gonad; ; right uterine tube; ; ganglionic eminence; ; ventricular zone; ; left ovary; ; right ovary; ; islet of Langerhans; ; body of pancreas; ; mucosa of transverse colon; ; spleen;
	Top expressed in
	ventricular zone; ; epiblast; ; ganglionic eminence; ; uterus; ; spleen; ; bone marrow; ; lens; ; thymus; ; islet of Langerhans; ; zone of skin;
	More reference expression data
	n/a
Gene ontology
Molecular function	virus receptor activity; structural constituent of ribosome; ribosome binding; laminin receptor activity; protein binding; RNA binding; laminin binding;
Cellular component	cytoplasm; cytosol; ribosome; membrane; plasma membrane; intracellular anatomical structure; small ribosomal subunit; extracellular exosome; nucleus; 90S preribosome; nucleoplasm; cytosolic small ribosomal subunit;
Biological process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; rRNA export from nucleus; viral entry into host cell; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; protein biosynthesis; viral process; rRNA processing; ribosomal small subunit assembly; cell adhesion; cytoplasmic translation;
	Sources:Amigo / QuickGO
Orthologs
	3921
	16785
	ENSG00000168028
	ENSMUSG00000032518
	P08865
	P14206
	NM_002295; NM_001304288
	NM_011029
	NP_001291217; NP_002286
	NP_035159
	Wikidata
View/Edit Human	View/Edit Mouse

40S ribosomal protein SA is a ribosomal protein that in humans is encoded by the RPSA gene. It also acts as a cell surface receptor, in particular for laminin, and is involved in several pathogenic processes.

This protein has been variously called Ribosomal protein SA; RPSA; LamR; LamR1; 37 kDa Laminin Receptor Precursor; 37LRP; 67 kDa Laminin Receptor; 67LR; 37/67 kDa Laminin Receptor; LRP/LR; LBP/p40; and p40 ribosome-associated protein. Ribosomal protein SA and RPSA are the approved name and symbol.