RRM2B

RRM2B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2VUX, 3HF1, 4DJN
Identifiers
Aliases	RRM2B, MTDPS8A, MTDPS8B, P53R2, ribonucleotide reductase regulatory TP53 inducible subunit M2B, RCDFRD
External IDs	OMIM: 604712; MGI: 2155865; HomoloGene: 56723; GeneCards: RRM2B; OMA:RRM2B - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	102,238,961 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	37,961,562 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; deltoid muscle; ; islet of Langerhans; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; germinal epithelium; ; tibialis anterior muscle; ; Skeletal muscle tissue of rectus abdominis; ; palpebral conjunctiva; ; pars reticulata;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; cardiac muscle tissue of left ventricle; ; Rostral migratory stream; ; sciatic nerve; ; cingulate gyrus; ; substantia nigra; ; habenula; ; iris;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; oxidoreductase activity; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;
Cellular component	mitochondrion; nucleus; nucleoplasm; cytoplasm; cytosol; ribonucleoside-diphosphate reductase complex;
Biological process	deoxyribonucleoside triphosphate metabolic process; renal system process; kidney development; response to oxidative stress; mitochondrial DNA replication; cellular response to DNA damage stimulus; deoxyribonucleotide biosynthetic process; DNA replication; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; response to amine; DNA repair; nucleobase-containing small molecule interconversion;
	Sources:Amigo / QuickGO
Orthologs
	50484
	382985
	ENSG00000048392
	ENSMUSG00000022292
	Q7LG56
	Q6PEE3
	NM_015713; NM_001172477; NM_001172478
	NM_199476; NM_001357022; NM_001357023
	NP_001165948; NP_001165949; NP_056528
	NP_955770; NP_001343951; NP_001343952
	Wikidata
View/Edit Human	View/Edit Mouse

Ribonucleotide-diphosphate reductase subunit M2 B is an enzyme that in humans is encoded by the RRM2B gene. The gene encoding the RRM2B protein is located on chromosome 8, at position 8q23.1. The gene and its products are also known by designations MTDPS8A, MTDPS8B, and p53R2.